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Pharmacodynamic Stance of Phytoconstituents as a Gastric Ulcer Protective Mechanism: An Overview

[ Vol. 22 , Issue. 5 ]


Manish Pal Singh*, Viney Chawla, Darpan Kaushik, Pooja A Chawla and Siddhraj Singh Sisodia   Pages 431 - 441 ( 11 )


Various traditional herbal plants have been associated with unique pharmacological actions. Natural parts as well as processed plant parts are known to possess gastro-protective and gastro- mucosal healing property. Motive of this review analysis is to explain the gastro-protective and gastro-mucosal healing property of different herbal plants and their constituents indigenous to various regions of the globe and elucidate mechanisms of the healing by their metabolic extracts. Moreover, an attempt shall be made to explicate the possible molecular pharmacological targets responsible for healing gastric ulcer activity. A thorough survey of literature has been carried out from various scientific resources and using keywords like peptic ulcer mechanism, gastro-protective agents, gastro-mucosal healing property, natural and processed herbal drugs preventing peptic ulcers. This article will present a running commentary on the prospects and potential of herbal plants exhibiting gastroprotective activity and gastro-mucosal healing property.


Gastric ulcer, gastroprotective, peptic ulcer, phytoconstituents, gastric mucus cell, cytoprotective.


Department of Pharmacology, Agra Public Pharmacy College, Agra, Uttar Pradesh, University Institute of Pharmaceutical Sciences and Research, Baba Farid University of Health Sciences, Faridkot, Punjab, Department of Pharmaceutical Chemistry, Agra Public Pharmacy College, Agra, Uttar Pradesh, Department of Pharmaceutical Chemistry and Analysis, ISF College of Pharmacy, Moga, Punjab, Department of Pharmacology, Faculty of Pharmacy, Bhupal Nobles University, Udaipur, Rajasthan

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