M. H. Tan and B. T. Teh Pages 895 - 897 ( 3 )
Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is a familial multi-tumor syndrome resulting from mutations in the HRPT2 tumor suppressor gene, which encodes a protein product named parafibromin. We review current knowledge of the renal manifestations of the HPT-JT syndrome, and examine recent advances in understanding the biological function of parafibromin.
hyperparathyroidism-jaw tumor (hpt-jt)syndrome, renal disorders, cystic kidney disease, mixed epithelial-stromal tumor, hrpt2 tumor suppressor, saccharomyces cerevisiae
Laboratory of Cancer Genetics, Van Andel Research Institute, 333 Bostwick Ave NE, Grand Rapids, MI 49503 (616) 234-5296, USA.